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Kantarjian et al53 assessed the efficacy and safety of dasatinib, as when compared with imatinib, for the primary-line therapy of CML-CP. Five hundred and nineteen sufferers with freshly diagnosed CML-CP had been randomly assigned to receive dasatinib at a dose of 100 mg as soon as day-to-day (259 clients) or imatinib in a dose of 400 mg the moment